SCREENING OF CHRONIC KIDNEY DISEASE BY ESTIMATED GLOMERULAR FILTRATION RATE AND ASSOCIATED FACTORS AMONG WEAVERS, GAMO ZONE, ETHIOPIA, SEPTEMBER, 2022 G.C.

Abstract

Background: Chronic kidney disease is a significant and growing health care burden globally. It has been suggested that CKD is directly linked to physical inactivity and sitting-related sedentary behaviour. Early intervention has slowed down the progression to more advanced stages of CKD, which typically gets worse with time. In high-risk populations, such as those with sedentary lifestyles, quick rates of progression, and more successful pharmacological therapies, CKD screening may be cost-effective. However, screening for CKD is infrequently done in developing countries, like Ethiopia, and abrupt kidney failure deaths are becoming more common. Therefore, this study was aimed to screen chronic kidney disease by estimated glomerular filtration rate and associated factors among weavers found in Gamo zone for an early detection of diseases. Objective: To screen chronic kidney disease by estimated glomerular filtration rate and associated factors among weavers, Gamo zone, Ethiopia, September, 2022 G.C. Methods: An institution-based cross-sectional study design was conducted among 251 adult weavers found in Gamo zone, Ethiopia, from February 1 to May 31, 2022 G.C. The level of serum creatinine was measured using semi-automated chemistry analyser mindray BA-88A. Then, eGFR was calculated using MDRD equations. Data analysis were done using SPSS version 21, and the factors associated with reduced eGFR were assessed using logistic regression. P values < 0.05 were considered as statistically significant. Results: In this study, 4.8% of participants had stage II kidney disease and 3.2% were diagnosed with CKD by MDRD equations. Hypertension, smoking, overweight and obesity were significantly associated with reduced glomerular filtration rate. The prevalence of Hypertension, pre-diabetics and diabetics were 38.2%, 62.1% and 12.3%, respectively.